Description
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Technical Profile:
Methamphetamine Hydrochloride (Analytical Reference Standard)
Certified Reference Material for Authorized Laboratory Use
This technical documentation provides verified analytical identification parameters and structural profiles for Methamphetamine Hydrochloride. This compound is synthesized, characterized, and cataloged strictly for use as an analytical reference standard in certified forensic laboratories, clinical toxicology research installations, and academic research institutions executing mass spectrometry calibration or in vitro neuroreceptor transport assays.
Technical Specifications & Product Identification Data
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- Systematic IUPAC Nomenclature: (2R)-N-methyl-1-phenylpropan-2-amine hydrochloride (isolated dextrorotatory enantiomer form)
- Standard CAS Registry Number: 51-57-0 (Hydrochloride Salt) | 537-46-2 (Free Base Form)
- Molecular Formula: C₁₀H₁₅N · HCl
- Exact Molar Mass: 149.23 g/mol (Base) | 185.70 g/mol (Refined Hydrochloride Salt)
- Physical Presentation: Transparent to translucent large crystalline structures, crystalline shards, or dense white crystalline powder
- Structural Classification: Substituted phenethylamine and chiral amphetamine derivative featuring a definitive N-methyl substitution on the aliphatic alkyl side chain.
Theoretical Pharmacology & Documented Adverse Effects
In controlled in vitro transport assays and cellular model configurations, Methamphetamine Hydrochloride acts as a potent central nervous system stimulant. Mechanistically, it functions as a high-affinity substrate-mediated releasing agent and competitive reuptake inhibitor for primary monoamine neurotransmitters:
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- Dopamine Transporters (DAT)
- Norepinephrine Transporters (NET)
- Serotonin Transporters (SERT)
By binding to and activating intracellular trace amine-associated receptor 1 (TAAR₁) and disrupting vesicular monoamine transporter 2 (VMAT₂) dynamics, it reverses the directional flow of transport proteins, causing immediate elevations of catecholamines inside the synaptic cleft.
Accidental, unauthorized, or uncontrolled exposure outside rigorous closed-system laboratory containment protocols presents severe, life-threatening physiological and psychological toxicity thresholds:
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- Cardiovascular Crises: Acute tachycardia, extreme peripheral vasoconstriction, severe hypertensive strain, myocardial infarction (heart attack), and heightened risks of intracranial hemorrhagic stroke.
- Neurological & Psychiatric Disruptions: Rapid drug-induced psychosis, severe psychomotor agitation, profound paranoia, core hyperthermia (dangerously elevated body temperature), and localized tonic-clonic convulsions.
- Dependency Profile: High liability for rapid, severe physical and psychological dependency.
Legal Status & International Regulatory Frameworks
The acquisition, storage, and handling of this compound are governed by strict international enforcement matrices and mandatory licensing frameworks to prevent diversion:
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- United Nations Conventions: Scheduled strictly under Schedule II of the 1971 Convention on Psychotropic Substances, enforcing rigorous international import/export quotas, pre-export notifications, and government-to-government authorizations.
- European Union: Classified uniformly as a heavily restricted narcotic drug across all EU Member States. National drug acts—such as Germany’s Betäubungsmittelgesetz (BtMG, Anlage II/III) and equivalent narcotic acts in France and the Netherlands—restrict distribution and possession exclusively to authorized medical manufacturers or state-licensed scientific laboratories holding specialized regulatory permits.
- United Kingdom: Classified strictly as a Class A controlled substance under the Misuse of Drugs Act 1971, carrying severe criminal penalties for unauthorized production, commercial supply, domestic transfer, or importation.
Authorized Research Use & Safety Warning
Methamphetamine Hydrochloride is an ultra-pure synthetic compound handled strictly as an analytical reference standard or reagent for accredited laboratory research, forensic profiling, and mass spectrometry calibration. It is not intended for unregulated human or veterinary consumption. By placing this item into your cart, Please ensure that you check the legality status of any product you purchase on our website as we cannot be held responsible for it.
